Cargando…

Evaluation of the Relative Intranasal Abuse Potential of a Hydrocodone Extended-Release Tablet Formulated with Abuse-Deterrence Technology in Nondependent, Recreational Opioid Users

OBJECTIVE: To assess the intranasal abuse potential of hydrocodone extended-release (ER) tablets developed with CIMA Abuse-Deterrence Technology compared with hydrocodone powder and hydrocodone bitartrate ER capsules (Zohydro ER, original formulation [HYD-OF]). DESIGN: Single-dose, randomized, doubl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bond, Mary, Schoedel, Kerri A, Rabinovich-Guilatt, Laura, Gasior, Maciej, Tracewell, William, Malamut, Richard, Ma, Yuju, Webster, Lynn R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	OPIOIDS & SUBSTANCE USE DISORDERS SECTION
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084602/ https://www.ncbi.nlm.nih.gov/pubmed/29016880 http://dx.doi.org/10.1093/pm/pnx133

Ejemplares similares

Abuse Potential with Oral Route of Administration of a Hydrocodone Extended-Release Tablet Formulated with Abuse-Deterrence Technology in Nondependent, Recreational Opioid Users
por: Darwish, Mona, et al.
Publicado: (2017)

Relative Bioavailability, Intranasal Abuse Potential, and Safety of Benzhydrocodone/Acetaminophen Compared with Hydrocodone Bitartrate/Acetaminophen in Recreational Drug Abusers
por: Guenther, Sven M, et al.
Publicado: (2018)

Human Abuse Potential of an Abuse-Deterrent (AD), Extended-Release (ER) Morphine Product Candidate (Morphine-ADER Injection-Molded Tablets) vs Extended-Release Morphine Administered Intranasally in Nondependent Recreational Opioid Users
por: Webster, Lynn R., et al.
Publicado: (2017)

Pharmacokinetics and Abuse Potential of Benzhydrocodone, a Novel Prodrug of Hydrocodone, After Intranasal Administration in Recreational Drug Users
por: Mickle, Travis C, et al.
Publicado: (2018)

A Randomized, Double-Blind, Double-Dummy, Placebo-Controlled, Intranasal Human Abuse Potential Study of Oxycodone ARIR, a Novel, Immediate-Release, Abuse-Deterrent Formulation
por: Webster, Lynn R, et al.
Publicado: (2019)

Human Abuse Potential of an Abuse-Deterrent (AD), Extended-Release (ER) Morphine Product Candidate (Morphine-ADER Injection-Molded Tablets) versus Extended-Release Morphine Administered Orally in Nondependent Recreational Opioid Users
por: Smith, Michael D., et al.
Publicado: (2017)

Effectiveness and Safety of Once-Daily Extended-Release Hydrocodone in Individuals Previously Receiving Immediate-Release Oxycodone for Chronic Pain
por: Pergolizzi, Joseph, et al.
Publicado: (2018)

Oral Abuse Potential, Pharmacokinetics, and Safety of Once-Daily, Single-Entity, Extended-Release Hydrocodone (HYD) in Recreational Opioid Users
por: Harris, Stephen C., et al.
Publicado: (2017)

Human Abuse Potential of the New Opioid Analgesic Molecule NKTR-181 Compared with Oxycodone
por: Webster, Lynn, et al.
Publicado: (2018)

Relative Abuse of Crush-Resistant Prescription Opioid Tablets via Alternative Oral Modes of Administration
por: Butler, Stephen F, et al.
Publicado: (2018)

A Randomized, Double-Blind, Double-Dummy Study to Evaluate the Intranasal Human Abuse Potential and Pharmacokinetics of a Novel Extended-Release Abuse-Deterrent Formulation of Oxycodone
por: Webster, Lynn R., et al.
Publicado: (2016)

Abuse Potential Study of ALO-02 (Extended-Release Oxycodone Surrounding Sequestered Naltrexone) Compared with Immediate-Release Oxycodone Administered Orally to Nondependent Recreational Opioid Users
por: Setnik, Beatrice, et al.
Publicado: (2017)

Correlates of patterns of cannabis use, abuse and dependence: evidence from two national surveys in Ireland
por: Millar, Seán R, et al.
Publicado: (2021)

Postmarketing Analysis of Misuse, Abuse, and Diversion of Xtampza ER
por: Geoffrey Severtson, Stevan, et al.
Publicado: (2020)

Assessment of Alcohol-Induced Dose Dumping with a Hydrocodone Bitartrate Extended-Release Tablet Formulated with CIMA(®) Abuse Deterrence Technology
por: Darwish, Mona, et al.
Publicado: (2015)

Are Prescription Opioids Driving the Opioid Crisis? Assumptions vs Facts
por: Rose, Mark Edmund
Publicado: (2018)

Validation of a Screening Risk Index for Serious Prescription Opioid-Induced Respiratory Depression or Overdose in a US Commercial Health Plan Claims Database
por: Zedler, Barbara K, et al.
Publicado: (2018)

A Novel Chronic Opioid Monitoring Tool to Assess Prescription Drug Steady State Levels in Oral Fluid
por: Shaparin, Naum, et al.
Publicado: (2017)

Laxatives Do Not Improve Symptoms of Opioid-Induced Constipation: Results of a Patient Survey
por: Emmanuel, Anton, et al.
Publicado: (2017)

Discrepancies Between Perceived Benefit of Opioids and Self-Reported Patient Outcomes
por: Goesling, Jenna, et al.
Publicado: (2018)

Long-Term Safety and Efficacy of Subcutaneous Methylnaltrexone in Patients with Opioid-Induced Constipation and Chronic Noncancer Pain: A Phase 3, Open-Label Trial
por: Webster, Lynn R., et al.
Publicado: (2017)

A Phase 2b, Randomized, Double-Blind Placebo-Controlled Study to Evaluate the Efficacy and Safety of Naldemedine for the Treatment of Opioid-Induced Constipation in Patients with Chronic Noncancer Pain
por: Webster, Lynn R, et al.
Publicado: (2017)

Risk Factors for Serious Prescription Opioid-Induced Respiratory Depression or Overdose: Comparison of Commercially Insured and Veterans Health Affairs Populations
por: Nadpara, Pramit A, et al.
Publicado: (2018)

Rational Urine Drug Monitoring in Patients Receiving Opioids for Chronic Pain: Consensus Recommendations
por: Argoff, Charles E, et al.
Publicado: (2018)

Measuring Opioid Withdrawal in a Phase 3 Study of a New Analgesic, NKTR-181 (Oxycodegol), in Patients with Moderate to Severe Chronic Low Back Pain
por: Henningfield, Jack E, et al.
Publicado: (2020)

Understanding Buprenorphine for Use in Chronic Pain: Expert Opinion
por: Webster, Lynn, et al.
Publicado: (2020)

Effect of Preoperative Opioid Use on Adverse Outcomes, Medical Spending, and Persistent Opioid Use Following Elective Total Joint Arthroplasty in the United States: A Large Retrospective Cohort Study of Administrative Claims Data
por: Blevins Peratikos, Meridith, et al.
Publicado: (2020)

Changes in Mortality Involving Extended-Release and Long-Acting Opioids After Implementation of a Risk Evaluation and Mitigation Strategy
por: Black, Joshua C, et al.
Publicado: (2020)

Trends in public attitudes to permitting cannabis for recreational use: analysis of Irish survey data since 2002
por: Mongan, Deirdre, et al.
Publicado: (2023)

Evaluation of Abuse and Route of Administration of Extended-Release Tapentadol Among Treatment-Seeking Individuals, as Captured by the Addiction Severity Index–Multimedia Version (ASI-MV)
por: Vosburg, Suzanne K, et al.
Publicado: (2019)

Assessment of the Abuse Potential of Cebranopadol in Nondependent Recreational Opioid Users: A Phase 1 Randomized Controlled Study
por: Göhler, Karin, et al.
Publicado: (2019)

Dancing with Deterrents: Understanding the Role of Abuse‐Deterrent Opioid Formulations and Naloxone in Managing Cancer Pain
por: Mitchell, Megan T.
Publicado: (2019)

Abuse Potential of Intravenous Oxycodone/Naloxone Solution in Nondependent Recreational Drug Users
por: Colucci, Salvatore V., et al.
Publicado: (2014)

Cultural adaptation of two school-based smoking prevention programs in Bogotá, Colombia
por: Sánchez-Franco, Sharon, et al.
Publicado: (2021)

Friendship Conflict, Drinking to Cope, and Alcohol-Related Problems: A Longitudinal Actor-Partner Interdependence Model
por: Mackinnon, Sean P., et al.
Publicado: (2022)

The relationship between substance use disorder and gambling disorder: A nationwide longitudinal health registry study
por: Leino, Tony, et al.
Publicado: (2021)

Does the suddenness matter? Antidepressant use before and after a spouse dies suddenly or expectedly of stroke
por: Einiö, Elina, et al.
Publicado: (2021)

Which illicit drugs are injected in Oslo? A study based on analysis of drug residues in used injection equipment and self-reported information
por: Gjerde, Hallvard, et al.
Publicado: (2021)

Increases in drug overdose deaths in Norway and the United States during the COVID-19 pandemic
por: Friedman, Joseph, et al.
Publicado: (2022)

Cannabis use disorder in relation to socioeconomic factors and psychiatric comorbidity: A cluster analysis of three million individuals born in 1970–2000
por: Rabiee, Rynaz, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_orvfqcqs28f3judhtoe8h2otru