Bioreactors for Decreasing the Growth of Brain Tumors

Malignant gliomas are the most common primary brain tumors. They are highly aggressive tumors characterized by a recurrence rate of virtually 100%. Despite significant advances in neuroimaging and neurosurgical techniques, the median survival time of patients with glioblastoma multiforme remains 12...

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Detalles Bibliográficos
Autores principales: Carroll, Rona S., Machluf, Marcelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2001
Materias:
Directions in Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084698/
https://www.ncbi.nlm.nih.gov/pubmed/12805667
http://dx.doi.org/10.1100/tsw.2001.25
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author Carroll, Rona S.
Machluf, Marcelle
author_facet Carroll, Rona S.
Machluf, Marcelle
author_sort Carroll, Rona S.
collection PubMed
description Malignant gliomas are the most common primary brain tumors. They are highly aggressive tumors characterized by a recurrence rate of virtually 100%. Despite significant advances in neuroimaging and neurosurgical techniques, the median survival time of patients with glioblastoma multiforme remains 12 to 18 months. Malignant gliomas are characterized by rapidly dividing cells, which invade into the normal brain, and a high degree of vascularity. Recent experimental evidence indicates that tumor-related angiogenesis contributes significantly to the malignant phenotype.
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spelling pubmed-60846982018-08-26 Bioreactors for Decreasing the Growth of Brain Tumors Carroll, Rona S. Machluf, Marcelle ScientificWorldJournal Directions in Science Malignant gliomas are the most common primary brain tumors. They are highly aggressive tumors characterized by a recurrence rate of virtually 100%. Despite significant advances in neuroimaging and neurosurgical techniques, the median survival time of patients with glioblastoma multiforme remains 12 to 18 months. Malignant gliomas are characterized by rapidly dividing cells, which invade into the normal brain, and a high degree of vascularity. Recent experimental evidence indicates that tumor-related angiogenesis contributes significantly to the malignant phenotype. TheScientificWorldJOURNAL 2001-05-01 /pmc/articles/PMC6084698/ /pubmed/12805667 http://dx.doi.org/10.1100/tsw.2001.25 Text en Copyright © 2001 Rona S. Carroll and Marcelle Machluf. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Directions in Science
Carroll, Rona S.
Machluf, Marcelle
Bioreactors for Decreasing the Growth of Brain Tumors
title Bioreactors for Decreasing the Growth of Brain Tumors
title_full Bioreactors for Decreasing the Growth of Brain Tumors
title_fullStr Bioreactors for Decreasing the Growth of Brain Tumors
title_full_unstemmed Bioreactors for Decreasing the Growth of Brain Tumors
title_short Bioreactors for Decreasing the Growth of Brain Tumors
title_sort bioreactors for decreasing the growth of brain tumors
topic Directions in Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084698/
https://www.ncbi.nlm.nih.gov/pubmed/12805667
http://dx.doi.org/10.1100/tsw.2001.25
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