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Comparison of two different methods of image analysis for the assessment of microglial activation in patients with multiple sclerosis using (R)-[N-methyl-carbon-11]PK11195

Chronic active multiple sclerosis (MS) lesions have a rim of activated microglia/macrophages (m/M) leading to ongoing tissue damage, and thus represent a potential treatment target. Activation of this innate immune response in MS has been visualized and quantified using PET imaging with [(11)C]-(R)-...

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Detalles Bibliográficos
Autores principales:	Kang, Yeona, Schlyer, David, Kaunzner, Ulrike W., Kuceyeski, Amy, Kothari, Paresh J., Gauthier, Susan A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084893/ https://www.ncbi.nlm.nih.gov/pubmed/30091993 http://dx.doi.org/10.1371/journal.pone.0201289

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