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Macular Thickness in Moderate to Severe Amblyopia
PURPOSE: To compare the macular retinal thickness of moderately to severely amblyopic eyes with non-amblyopic eyes as controls. METHODS: This case control study was conducted on 56 children aged 4 to 10 years old (64.3% female subjects). Twenty-eight children had unilateral amblyopia (28 amblyopic e...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Korean Ophthalmological Society
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085182/ https://www.ncbi.nlm.nih.gov/pubmed/30091310 http://dx.doi.org/10.3341/kjo.2017.0101 |
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author | Rajavi, Zhale Sabbaghi, Hamideh Behradfar, Narges Yaseri, Mehdi Aghazadeh Amiri, Mohammad Faghihi, Mohammad |
author_facet | Rajavi, Zhale Sabbaghi, Hamideh Behradfar, Narges Yaseri, Mehdi Aghazadeh Amiri, Mohammad Faghihi, Mohammad |
author_sort | Rajavi, Zhale |
collection | PubMed |
description | PURPOSE: To compare the macular retinal thickness of moderately to severely amblyopic eyes with non-amblyopic eyes as controls. METHODS: This case control study was conducted on 56 children aged 4 to 10 years old (64.3% female subjects). Twenty-eight children had unilateral amblyopia (28 amblyopic eyes as cases and 28 normal fellow eyes as internal controls) and 28 children had normal visual acuity in both eyes and were considered as external controls (n = 56 eyes). Among our cases, 14 had strabismic amblyopia and 14 had anisometropic amblyopia. Macular retinal thickness was measured using optical coherence tomography at the center and in 1-, 3-, and 6-mm rings. RESULTS: Best-corrected visual acuity of the amblyopic eyes was less than that of the internal and external controls, and the best-corrected visual acuity of their fellow eyes was also less than that of the external controls. Thickness of the central macula and a 1-mm ring area in the amblyopic eyes was higher than that of both internal and external controls. Difference of central macular thickness ≥20 µm between two eyes of the amblyopic children was significantly more than non-amblyopic subjects. CONCLUSIONS: Based on the results of this study, the macular retinal thickness was significantly higher in moderate to severe amblyopic eyes compared to their fellow eyes and external controls. This might be due to macular developmental disorders in amblyopic eyes. Therefore, optical coherence tomography imaging is recommended if subtle macular abnormalities are suspected in moderate to severe amblyopic eyes. |
format | Online Article Text |
id | pubmed-6085182 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The Korean Ophthalmological Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-60851822018-08-14 Macular Thickness in Moderate to Severe Amblyopia Rajavi, Zhale Sabbaghi, Hamideh Behradfar, Narges Yaseri, Mehdi Aghazadeh Amiri, Mohammad Faghihi, Mohammad Korean J Ophthalmol Original Article PURPOSE: To compare the macular retinal thickness of moderately to severely amblyopic eyes with non-amblyopic eyes as controls. METHODS: This case control study was conducted on 56 children aged 4 to 10 years old (64.3% female subjects). Twenty-eight children had unilateral amblyopia (28 amblyopic eyes as cases and 28 normal fellow eyes as internal controls) and 28 children had normal visual acuity in both eyes and were considered as external controls (n = 56 eyes). Among our cases, 14 had strabismic amblyopia and 14 had anisometropic amblyopia. Macular retinal thickness was measured using optical coherence tomography at the center and in 1-, 3-, and 6-mm rings. RESULTS: Best-corrected visual acuity of the amblyopic eyes was less than that of the internal and external controls, and the best-corrected visual acuity of their fellow eyes was also less than that of the external controls. Thickness of the central macula and a 1-mm ring area in the amblyopic eyes was higher than that of both internal and external controls. Difference of central macular thickness ≥20 µm between two eyes of the amblyopic children was significantly more than non-amblyopic subjects. CONCLUSIONS: Based on the results of this study, the macular retinal thickness was significantly higher in moderate to severe amblyopic eyes compared to their fellow eyes and external controls. This might be due to macular developmental disorders in amblyopic eyes. Therefore, optical coherence tomography imaging is recommended if subtle macular abnormalities are suspected in moderate to severe amblyopic eyes. The Korean Ophthalmological Society 2018-08 2018-08-08 /pmc/articles/PMC6085182/ /pubmed/30091310 http://dx.doi.org/10.3341/kjo.2017.0101 Text en © 2018 The Korean Ophthalmological Society http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Rajavi, Zhale Sabbaghi, Hamideh Behradfar, Narges Yaseri, Mehdi Aghazadeh Amiri, Mohammad Faghihi, Mohammad Macular Thickness in Moderate to Severe Amblyopia |
title | Macular Thickness in Moderate to Severe Amblyopia |
title_full | Macular Thickness in Moderate to Severe Amblyopia |
title_fullStr | Macular Thickness in Moderate to Severe Amblyopia |
title_full_unstemmed | Macular Thickness in Moderate to Severe Amblyopia |
title_short | Macular Thickness in Moderate to Severe Amblyopia |
title_sort | macular thickness in moderate to severe amblyopia |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085182/ https://www.ncbi.nlm.nih.gov/pubmed/30091310 http://dx.doi.org/10.3341/kjo.2017.0101 |
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