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Systematic identification of non-coding pharmacogenomic landscape in cancer

Emerging evidence has shown long non-coding RNAs (lncRNAs) play important roles in cancer drug response. Here we report a lncRNA pharmacogenomic landscape by integrating multi-dimensional genomic data of 1005 cancer cell lines and drug response data of 265 anti-cancer compounds. Using Elastic Net (E...

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Detalles Bibliográficos
Autores principales:	Wang, Yue, Wang, Zehua, Xu, Jieni, Li, Jiang, Li, Song, Zhang, Min, Yang, Da
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085336/ https://www.ncbi.nlm.nih.gov/pubmed/30093685 http://dx.doi.org/10.1038/s41467-018-05495-9

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