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Increased glutamine anabolism sensitizes non-small cell lung cancer to gefitinib treatment

To better understand the resistance mechanism of non-small cell lung cancers (NSCLCs) to gefitinib, the metabolic profiles of gefitinib-resistant A549 cells and gefitinib-sensitive PC-9 cells were analyzed with a metabolomics analytical platform. A549 and PC-9 cells exhibited significant differences...

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Detalles Bibliográficos
Autores principales:	Wang, Liang, Peng, Wen, Wu, Tianming, Deng, Pengchi, Zhao, Ying-Lan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085389/ https://www.ncbi.nlm.nih.gov/pubmed/30109143 http://dx.doi.org/10.1038/s41420-018-0086-x

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