Circulating T Cell Subpopulations Correlate With Immune Responses at the Tumor Site and Clinical Response to PD1 Inhibition in Non-Small Cell Lung Cancer

Agents targeting the PD1–PDL1 axis have transformed cancer therapy. Factors that influence clinical response to PD1–PDL1 inhibitors include tumor mutational burden, immune infiltration of the tumor, and local PDL1 expression. To identify peripheral correlates of the anti-tumor immune response in the...

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Detalles Bibliográficos
Autores principales: Manjarrez-Orduño, Nataly, Menard, Laurence C., Kansal, Selena, Fischer, Paul, Kakrecha, Bijal, Jiang, Can, Cunningham, Mark, Greenawalt, Danielle, Patel, Vishal, Yang, Minghui, Golhar, Ryan, Carman, Julie A., Lezhnin, Sergey, Dai, Hongyue, Kayne, Paul S., Suchard, Suzanne J., Bernstein, Steven H., Nadler, Steven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085412/
https://www.ncbi.nlm.nih.gov/pubmed/30123214
http://dx.doi.org/10.3389/fimmu.2018.01613

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