ASD-Associated De Novo Mutations in Five Actin Regulators Show Both Shared and Distinct Defects in Dendritic Spines and Inhibitory Synapses in Cultured Hippocampal Neurons

Many actin cytoskeleton-regulating proteins control dendritic spine morphology and density, which are cellular features often altered in autism spectrum disorder (ASD). Recent studies using animal models show that autism-related behavior can be rescued by either manipulating actin regulators or by r...

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Detalles Bibliográficos
Autores principales: Hlushchenko, Iryna, Khanal, Pushpa, Abouelezz, Amr, Paavilainen, Ville O., Hotulainen, Pirta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085419/
https://www.ncbi.nlm.nih.gov/pubmed/30123108
http://dx.doi.org/10.3389/fncel.2018.00217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085419/
https://www.ncbi.nlm.nih.gov/pubmed/30123108
http://dx.doi.org/10.3389/fncel.2018.00217

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