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NAD-Glycohydrolase Depletes Intracellular NAD(+) and Inhibits Acidification of Autophagosomes to Enhance Multiplication of Group A Streptococcus in Endothelial Cells
Group A Streptococcus (GAS) is a human pathogen causing a wide spectrum of diseases, from mild pharyngitis to life-threatening necrotizing fasciitis. GAS has been shown to evade host immune killing by invading host cells. However, how GAS resists intracellular killing by endothelial cells is still u...
Autores principales: | Hsieh, Cheng-Lu, Huang, Hsuan-Min, Hsieh, Shu-Ying, Zheng, Po-Xing, Lin, Yee-Shin, Chiang-Ni, Chuan, Tsai, Pei-Jane, Wang, Shu-Ying, Liu, Ching-Chuan, Wu, Jiunn-Jong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085451/ https://www.ncbi.nlm.nih.gov/pubmed/30123194 http://dx.doi.org/10.3389/fmicb.2018.01733 |
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