Effect of Cholesterol on Membrane Fluidity and Association of Aβ Oligomers and Subsequent Neuronal Damage: A Double-Edged Sword

Background: The beta-amyloid peptide (Aβ) involved in Alzheimer’s disease (AD) has been described to associate/aggregate on the cell surface disrupting the membrane through pore formation and breakage. However, molecular determinants involved for this interaction (e.g., some physicochemical properti...

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Detalles Bibliográficos
Autores principales: Fernández-Pérez, Eduardo J., Sepúlveda, Fernando J., Peters, Christian, Bascuñán, Denisse, Riffo-Lepe, Nicolás O., González-Sanmiguel, Juliana, Sánchez, Susana A., Peoples, Robert W., Vicente, Benjamín, Aguayo, Luis G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085471/
https://www.ncbi.nlm.nih.gov/pubmed/30123122
http://dx.doi.org/10.3389/fnagi.2018.00226

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