Cargando…

Proapoptotic Cyclic Peptide BC71 Targets Cell-Surface GRP78 and Functions as an Anticancer Therapeutic in Mice

Glucose regulated protein 78 kDa (GRP78) is a recently emerged target for cancer therapy and a biomarker for cancer prognosis. Overexpression of GRP78 is observed in many types of cancers, with the cell-surface GRP78 being preferentially present in cancer cells and cancer blood vessel endothelial ce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kao, Chieh, Chandna, Ritu, Ghode, Abhijeet, Dsouza, Charlotte, Chen, Mo, Larsson, Andreas, Lim, Siau Hoi, Wang, Minjun, Cao, Zhonglian, Zhu, Yizhun, Anand, Ganesh S., Ge, Ruowen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085501/ https://www.ncbi.nlm.nih.gov/pubmed/29907328 http://dx.doi.org/10.1016/j.ebiom.2018.06.004

Ejemplares similares

Cell Surface GRP78 as a Death Receptor and an Anticancer Drug Target
por: Ge, Ruowen, et al.
Publicado: (2019)

ISM1 protects lung homeostasis via cell-surface GRP78-mediated alveolar macrophage apoptosis
por: Lam, Terence Y. W., et al.
Publicado: (2022)

GRP78 in lung cancer
por: Xia, Shengkai, et al.
Publicado: (2021)

Mitochondrial metabolic regulation by GRP78
por: Prasad, Manoj, et al.
Publicado: (2017)

Differential requirement of GRP94 and GRP78 in mammary gland development
por: Zhu, Genyuan, et al.
Publicado: (2014)

Ultrasensitive Detection of GRP78 in Exosomes and Observation of Migration and Proliferation of Cancer Cells by Application of GRP78-Containing Exosomes
por: Tsurusawa, Naoko, et al.
Publicado: (2022)

GRP78-CAR T cell effector function against solid and brain tumors is controlled by GRP78 expression on T cells
por: Ibanez, Jorge, et al.
Publicado: (2023)

Grp78 promotes the invasion of hepatocellular carcinoma
por: Su, Rongjian, et al.
Publicado: (2010)

GRP78 at the Centre of the Stage in Cancer and Neuroprotection
por: Casas, Caty
Publicado: (2017)

Targeting the GRP78 Pathway for Cancer Therapy
por: Lu, Guanhua, et al.
Publicado: (2020)

GRP78: A cell's response to stress
por: Ibrahim, Ibrahim M., et al.
Publicado: (2019)

Enterovirus 71 induces dsRNA/PKR-dependent cytoplasmic redistribution of GRP78/BiP to promote viral replication
por: Jheng, Jia-Rong, et al.
Publicado: (2016)

Expression and release of glucose-regulated protein-78 (GRP78) in multiple myeloma
por: Steiner, Normann, et al.
Publicado: (2017)

The Endogenous GRP78 Interactome in Human Head and Neck Cancers: A Deterministic Role of Cell Surface GRP78 in Cancer Stemness
por: Chen, Hsin-Ying, et al.
Publicado: (2018)

Involvement of Membrane GRP78 in Trophoblastic Cell Fusion
por: Fradet, Sarah, et al.
Publicado: (2012)

The Interplay between Glucose-Regulated Protein 78 (GRP78) and Steroids in the Reproductive System
por: Hebert-Schuster, Marylise, et al.
Publicado: (2018)

The chaperone GRP78 is a host auxiliary factor for SARS-CoV-2 and GRP78 depleting antibody blocks viral entry and infection
por: Carlos, Anthony J., et al.
Publicado: (2021)

Upregulation of Phosphorylated HSP27, PRDX2, GRP75, GRP78 and GRP94 in Acquired Middle Ear Cholesteatoma Growth
por: Ho, Kuen Yao, et al.
Publicado: (2013)

Co-downregulation of GRP78 and GRP94 Induces Apoptosis and Inhibits Migration in Prostate Cancer Cells
por: Lu, Tong, et al.
Publicado: (2019)

GRP78 inhibits macrophage adhesion via SR-A
por: Bai, Hui, et al.
Publicado: (2014)

Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs
por: Hughes, Scott J., et al.
Publicado: (2016)

The meta and bioinformatics analysis of GRP78 expression in gastric cancer
por: Zheng, Hua-Chuan, et al.
Publicado: (2017)

GRP78 Is a Targetable Receptor on Cancer and Stromal Cells
por: Araujo, Nathalia, et al.
Publicado: (2018)

GRP78 targeting: Hitting two birds with a stone
por: Elfiky, Abdo A., et al.
Publicado: (2020)

GRP 78 antibodies are associated with clinical phenotype in neuromyelitis optica
por: Shimizu, Fumitaka, et al.
Publicado: (2019)

ILDR2 stabilization is regulated by its interaction with GRP78
por: Watanabe, Kazuhisa, et al.
Publicado: (2021)

COVID-19, Obesity, and GRP78: Unraveling the Pathological Link
por: Shin, Jihoon, et al.
Publicado: (2023)

Physiological Roles of the Autoantibodies to the 78-Kilodalton Glucose-Regulated Protein (GRP78) in Cancer and Autoimmune Diseases
por: Gonzalez-Gronow, Mario, et al.
Publicado: (2022)

Down-regulation of GRP78 in human glaucomatous trabecular meshwork cells
por: Chai, Fang, et al.
Publicado: (2010)

The Cell Surface GRP78 Facilitates the Invasion of Hepatocellular Carcinoma Cells
por: Zhang, Xiu-Xiu, et al.
Publicado: (2013)

Different Roles of GRP78 on Cell Proliferation and Apoptosis in Cartilage Development
por: Xiong, Zhangyuan, et al.
Publicado: (2015)

Acetylation modification regulates GRP78 secretion in colon cancer cells
por: Li, Zongwei, et al.
Publicado: (2016)

Correction: Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs
por: Hughes, Scott J, et al.
Publicado: (2016)

Data for peptide-binding assay with oriented immobilization of GRP78 in Biacore
por: Wang, Sheng-Hung, et al.
Publicado: (2016)

The deubiquitylase OTUD3 stabilizes GRP78 and promotes lung tumorigenesis
por: Du, Tongde, et al.
Publicado: (2019)

Cell surface GRP78 promotes stemness in normal and neoplastic cells
por: Conner, Clay, et al.
Publicado: (2020)

COVID19 associated mucormycosis: Is GRP78 a possible link?
por: Gumashta, Jyotsna, et al.
Publicado: (2021)

Characterizing Cell Stress and GRP78 in Glioma to Enhance Tumor Treatment
por: Liu, Kristie, et al.
Publicado: (2020)

Scratching the Surface—An Overview of the Roles of Cell Surface GRP78 in Cancer
por: Chen, Jack, et al.
Publicado: (2022)

Emerging role of LETM1/GRP78 axis in lung cancer
por: Tran, Quangdon, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_58uskvrh6cmium89gqdqbf85eb