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Calcium-activated Chloride Channel Regulator 1 (CLCA1) Controls Mucus Expansion in Colon by Proteolytic Activity
Many epithelial surfaces of the body are covered with protective mucus, and disrupted mucus homeostasis is coupled to diseases such as ulcerative colitis, helminth infection, cystic fibrosis, and chronic obstructive lung disease. However, little is known how a balanced mucus system is maintained. By...
Autores principales: | Nyström, Elisabeth E.L., Birchenough, George M.H., van der Post, Sjoerd, Arike, Liisa, Gruber, Achim D., Hansson, Gunnar C., Johansson, Malin E.V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085540/ https://www.ncbi.nlm.nih.gov/pubmed/29885864 http://dx.doi.org/10.1016/j.ebiom.2018.05.031 |
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