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In-Silico Characterization and in-Vivo Validation of Albiziasaponin-A, Iso-Orientin, and Salvadorin Using a Rat Model of Alzheimer's Disease
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by dementia, excessive acetylcholinesterase (AChE) activity, formation of neurotoxic amyloid plaque, and tau protein aggregation. Based on literature survey, we have shortlisted three important target proteins (AChE, COX2, a...
Autores principales: | Rasool, Mahmood, Malik, Arif, Waquar, Sulayman, Tul-Ain, Qura, Jafar, Tassadaq H., Rasool, Rabia, Kalsoom, Aasia, Ghafoor, Muhammad A., Sehgal, Sheikh A., Gauthaman, Kalamegam, Naseer, Muhammad I., Al-Qahtani, Mohammed H., Pushparaj, Peter N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085546/ https://www.ncbi.nlm.nih.gov/pubmed/30123124 http://dx.doi.org/10.3389/fphar.2018.00730 |
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