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Anti-Tumour Necrosis Factor Therapy for Dupuytren's Disease: A Randomised Dose Response Proof of Concept Phase 2a Clinical Trial

BACKGROUND: Dupuytren's disease is a common fibrotic condition of the hand that causes irreversible flexion contractures of the fingers, with no approved therapy for early stage disease. Our previous analysis of surgically-excised tissue defined tumour necrosis factor (TNF) as a potential thera...

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Detalles Bibliográficos
Autores principales:	Nanchahal, Jagdeep, Ball, Catherine, Davidson, Dominique, Williams, Lynn, Sones, William, McCann, Fiona E., Cabrita, Marisa, Swettenham, Jennifer, Cahoon, Neil J., Copsey, Bethan, Anne Francis, E., Taylor, Peter C., Black, Joanna, Barber, Vicki S., Dutton, Susan, Feldmann, Marc, Lamb, Sarah E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085556/ https://www.ncbi.nlm.nih.gov/pubmed/29983350 http://dx.doi.org/10.1016/j.ebiom.2018.06.022

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