Short-Term Hypoxia Dampens Inflammation in vivo via Enhanced Adenosine Release and Adenosine 2B Receptor Stimulation

Hypoxia and inflammation are closely intertwined phenomena. Critically ill patients often suffer from systemic inflammatory conditions and concurrently experience short-lived hypoxia. We evaluated the effects of short-term hypoxia on systemic inflammation, and show that it potently attenuates pro-in...

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Detalles Bibliográficos
Autores principales: Kiers, Dorien, Wielockx, Ben, Peters, Esther, van Eijk, Lucas T., Gerretsen, Jelle, John, Aaron, Janssen, Emmy, Groeneveld, Rianne, Peters, Mara, Damen, Lars, Meneses, Ana M., Krüger, Anja, Langereis, Jeroen D., Zomer, Aldert L., Blackburn, Michael R., Joosten, Leo A., Netea, Mihai G., Riksen, Niels P., van der Hoeven, Johannes G., Scheffer, Gert-Jan, Eltzschig, Holger K., Pickkers, Peter, Kox, Matthijs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085583/
https://www.ncbi.nlm.nih.gov/pubmed/29983349
http://dx.doi.org/10.1016/j.ebiom.2018.06.021

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