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Differential relationship between waist circumference and mortality according to age, sex, and body mass index in Korean with age of 30–90 years; a nationwide health insurance database study

BACKGROUND: A recent concept is that obesity, assessed by body mass index (BMI), is not always a sign of poor health. Thus, in order to use obesity metrics in clinical decision making, it is important to clarify the relationship between waist circumference (WC), a proxy for abdominal obesity, and mo...

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Autores principales: Cho, Geum Joon, Yoo, Hye Jin, Hwang, Soon Young, Choi, Jun, Lee, Kyu-Min, Choi, Kyung Mook, Baik, Sei Hyun, Han, Sung Won, Kim, Tak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085614/
https://www.ncbi.nlm.nih.gov/pubmed/30092838
http://dx.doi.org/10.1186/s12916-018-1114-7
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author Cho, Geum Joon
Yoo, Hye Jin
Hwang, Soon Young
Choi, Jun
Lee, Kyu-Min
Choi, Kyung Mook
Baik, Sei Hyun
Han, Sung Won
Kim, Tak
author_facet Cho, Geum Joon
Yoo, Hye Jin
Hwang, Soon Young
Choi, Jun
Lee, Kyu-Min
Choi, Kyung Mook
Baik, Sei Hyun
Han, Sung Won
Kim, Tak
author_sort Cho, Geum Joon
collection PubMed
description BACKGROUND: A recent concept is that obesity, assessed by body mass index (BMI), is not always a sign of poor health. Thus, in order to use obesity metrics in clinical decision making, it is important to clarify the relationship between waist circumference (WC), a proxy for abdominal obesity, and mortality. METHODS: Data were used from 8,796,759 subjects aged between 30 and 90 years, who had participated in the Korea National Health Screening Examination between January 1, 2009 and December 31, 2009 and survived at least 1 year post screening. Data from a mean follow-up time of an additional 5.3 years (time at risk) were analyzed for the relationship between WC and mortality according to age, sex, and BMI category. RESULTS: An increased WC of more than 90 cm in men and 85 cm in women showed a definite negative influence on mortality. However, the detailed relationship between WC and mortality was J-shaped or U-shaped according to age, sex, and BMI category. In the normal BMI group, the optimal WC range with the lowest mortality was < 70 cm in men and 70–75 cm in women, whereas in obese individuals a WC between 80 and 90 cm in men and 75 and 85 cm in women showed the lowest mortality. The association between increased WC and higher mortality tended to be more obvious in normal-weight women than in normal-weight men or obese women. Furthermore, in normal-weight and obese women, the effect of increased WC on mortality was more critical for subjects aged < 60 years rather than those aged ≥ 60 years. CONCLUSIONS: Abdominal obesity, as measured by WC, showed a significant negative association on mortality, and its association with mortality was different according to age, sex, and BMI category. Therefore, WC should be considered in the assessment of obesity-related health risks, and individualized cut-off points for the definition of a healthy WC according to age, sex, and BMI category are necessary. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12916-018-1114-7) contains supplementary material, which is available to authorized users.
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spelling pubmed-60856142018-08-16 Differential relationship between waist circumference and mortality according to age, sex, and body mass index in Korean with age of 30–90 years; a nationwide health insurance database study Cho, Geum Joon Yoo, Hye Jin Hwang, Soon Young Choi, Jun Lee, Kyu-Min Choi, Kyung Mook Baik, Sei Hyun Han, Sung Won Kim, Tak BMC Med Research Article BACKGROUND: A recent concept is that obesity, assessed by body mass index (BMI), is not always a sign of poor health. Thus, in order to use obesity metrics in clinical decision making, it is important to clarify the relationship between waist circumference (WC), a proxy for abdominal obesity, and mortality. METHODS: Data were used from 8,796,759 subjects aged between 30 and 90 years, who had participated in the Korea National Health Screening Examination between January 1, 2009 and December 31, 2009 and survived at least 1 year post screening. Data from a mean follow-up time of an additional 5.3 years (time at risk) were analyzed for the relationship between WC and mortality according to age, sex, and BMI category. RESULTS: An increased WC of more than 90 cm in men and 85 cm in women showed a definite negative influence on mortality. However, the detailed relationship between WC and mortality was J-shaped or U-shaped according to age, sex, and BMI category. In the normal BMI group, the optimal WC range with the lowest mortality was < 70 cm in men and 70–75 cm in women, whereas in obese individuals a WC between 80 and 90 cm in men and 75 and 85 cm in women showed the lowest mortality. The association between increased WC and higher mortality tended to be more obvious in normal-weight women than in normal-weight men or obese women. Furthermore, in normal-weight and obese women, the effect of increased WC on mortality was more critical for subjects aged < 60 years rather than those aged ≥ 60 years. CONCLUSIONS: Abdominal obesity, as measured by WC, showed a significant negative association on mortality, and its association with mortality was different according to age, sex, and BMI category. Therefore, WC should be considered in the assessment of obesity-related health risks, and individualized cut-off points for the definition of a healthy WC according to age, sex, and BMI category are necessary. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12916-018-1114-7) contains supplementary material, which is available to authorized users. BioMed Central 2018-08-10 /pmc/articles/PMC6085614/ /pubmed/30092838 http://dx.doi.org/10.1186/s12916-018-1114-7 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Cho, Geum Joon
Yoo, Hye Jin
Hwang, Soon Young
Choi, Jun
Lee, Kyu-Min
Choi, Kyung Mook
Baik, Sei Hyun
Han, Sung Won
Kim, Tak
Differential relationship between waist circumference and mortality according to age, sex, and body mass index in Korean with age of 30–90 years; a nationwide health insurance database study
title Differential relationship between waist circumference and mortality according to age, sex, and body mass index in Korean with age of 30–90 years; a nationwide health insurance database study
title_full Differential relationship between waist circumference and mortality according to age, sex, and body mass index in Korean with age of 30–90 years; a nationwide health insurance database study
title_fullStr Differential relationship between waist circumference and mortality according to age, sex, and body mass index in Korean with age of 30–90 years; a nationwide health insurance database study
title_full_unstemmed Differential relationship between waist circumference and mortality according to age, sex, and body mass index in Korean with age of 30–90 years; a nationwide health insurance database study
title_short Differential relationship between waist circumference and mortality according to age, sex, and body mass index in Korean with age of 30–90 years; a nationwide health insurance database study
title_sort differential relationship between waist circumference and mortality according to age, sex, and body mass index in korean with age of 30–90 years; a nationwide health insurance database study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085614/
https://www.ncbi.nlm.nih.gov/pubmed/30092838
http://dx.doi.org/10.1186/s12916-018-1114-7
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