Chimeric Plasmodium falciparum parasites expressing Plasmodium vivax circumsporozoite protein fail to produce salivary gland sporozoites

BACKGROUND: Rodent malaria parasites where the gene encoding circumsporozoite protein (CSP) has been replaced with csp genes from the human malaria parasites, Plasmodium falciparum or Plasmodium vivax, are used as pre-clinical tools to evaluate CSP vaccines in vivo. These chimeric rodent parasites p...

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Detalles Bibliográficos
Autores principales: Marin-Mogollon, Catherin, van Pul, Fiona J. A., Miyazaki, Shinya, Imai, Takashi, Ramesar, Jai, Salman, Ahmed M., Winkel, Beatrice M. F., Othman, Ahmad Syibli, Kroeze, Hans, Chevalley-Maurel, Severine, Reyes-Sandoval, Arturo, Roestenberg, Meta, Franke-Fayard, Blandine, Janse, Chris J., Khan, Shahid M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085629/
https://www.ncbi.nlm.nih.gov/pubmed/30092798
http://dx.doi.org/10.1186/s12936-018-2431-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085629/
https://www.ncbi.nlm.nih.gov/pubmed/30092798
http://dx.doi.org/10.1186/s12936-018-2431-1

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