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Multiple determinants and consequences of cohesion fatigue in mammalian cells

Cells delayed in metaphase with intact mitotic spindles undergo cohesion fatigue, where sister chromatids separate asynchronously, while cells remain in mitosis. Cohesion fatigue requires release of sister chromatid cohesion. However, the pathways that breach sister chromatid cohesion during cohesio...

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Detalles Bibliográficos
Autores principales: Sapkota, Hem, Wasiak, Emilia, Daum, John R., Gorbsky, Gary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085821/
https://www.ncbi.nlm.nih.gov/pubmed/29846129
http://dx.doi.org/10.1091/mbc.E18-05-0315