Mismatch repair gene mutations lead to lynch syndrome colorectal cancer in rhesus macaques

Colorectal cancer accounts for a substantial number of deaths each year worldwide. Lynch Syndrome is a genetic form of colorectal cancer (CRC) caused by inherited mutations in DNA mismatch repair (MMR) genes. Although researchers have developed mouse models of Lynch Syndrome through targeted mutagen...

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Detalles Bibliográficos
Autores principales: Dray, Beth K., Raveendran, Muthuswamy, Harris, R. Alan, Benavides, Fernando, Gray, Stanton B., Perez, Carlos J., McArthur, Mark J., Williams, Lawrence E., Baze, Wallace B., Doddapaneni, Harsha, Muzny, Donna M., Abee, Christian R., Rogers, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086002/
https://www.ncbi.nlm.nih.gov/pubmed/30108684
http://dx.doi.org/10.18632/genesandcancer.170

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