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Desmoplasia in pancreatic ductal adenocarcinoma: insight into pathological function and therapeutic potential

Extensive desmoplasia is a prominent feature of the pancreatic ductal adenocarcinoma (PDAC) microenvironment. Initially, studies demonstrated that desmoplasia promotes proliferation, invasion and chemoresistance in PDAC cells. While these findings suggested the therapeutic potential of targeting des...

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Detalles Bibliográficos
Autores principales:	Cannon, Andrew, Thompson, Christopher, Hall, Bradley R., Jain, Maneesh, Kumar, Sushil, Batra, Surinder K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086006/ https://www.ncbi.nlm.nih.gov/pubmed/30108679 http://dx.doi.org/10.18632/genesandcancer.171

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