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Increased Axonal Bouton Stability during Learning in the Mouse Model of MECP2 Duplication Syndrome
MECP2 duplication syndrome is an X-linked form of syndromic autism caused by genomic duplication of the region encoding methyl-CpG-binding protein 2 (MECP2). Mice overexpressing MECP2 demonstrate social impairment, behavioral inflexibility, and altered patterns of learning and memory. Previous work...
Autores principales: | Ash, Ryan T., Fahey, Paul G., Park, Jiyoung, Zoghbi, Huda Y., Smirnakis, Stelios M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086213/ https://www.ncbi.nlm.nih.gov/pubmed/30105297 http://dx.doi.org/10.1523/ENEURO.0056-17.2018 |
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