Spontaneous point mutations in the capsule synthesis locus leading to structural and functional changes of the capsule in serogroup A meningococcal populations

Whole genome sequencing analysis of 100 Neisseria meningitidis serogroup A isolates has revealed that the csaABCD-ctrABCD-ctrEF capsule polysaccharide synthesis locus represents a spontaneous point mutation hotspot. Structural and functional properties of the capsule of 11 carriage and two disease i...

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Detalles Bibliográficos
Autores principales: Ispasanie, Emma, Micoli, Francesca, Lamelas, Araceli, Keller, Dominique, Berti, Francesco, De Riccio, Riccardo, Di Benedettoi, Roberta, Rondini, Simona, Pluschke, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086313/
https://www.ncbi.nlm.nih.gov/pubmed/30067453
http://dx.doi.org/10.1080/21505594.2018.1467710

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