Macrophage CD40 plays a minor role in obesity-induced metabolic dysfunction

Obesity is a low-grade inflammatory disease that increases the risk for metabolic disorders. CD40-CD40L signaling plays a central role in obesity-induced inflammation. Genetic deficiency of CD40L in diet-induced obesity (DIO) ameliorates adipose tissue inflammation, hepatic steatosis and increases i...

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Detalles Bibliográficos
Autores principales: Aarts, Suzanne A. B. M., Reiche, Myrthe E., den Toom, Myrthe, Beckers, Linda, Gijbels, Marion J. J., Gerdes, Norbert, de Winther, Menno P. J., Lutgens, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086432/
https://www.ncbi.nlm.nih.gov/pubmed/30096208
http://dx.doi.org/10.1371/journal.pone.0202150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086432/
https://www.ncbi.nlm.nih.gov/pubmed/30096208
http://dx.doi.org/10.1371/journal.pone.0202150

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