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Macrophage CD40 plays a minor role in obesity-induced metabolic dysfunction
Obesity is a low-grade inflammatory disease that increases the risk for metabolic disorders. CD40-CD40L signaling plays a central role in obesity-induced inflammation. Genetic deficiency of CD40L in diet-induced obesity (DIO) ameliorates adipose tissue inflammation, hepatic steatosis and increases i...
Autores principales: | Aarts, Suzanne A. B. M., Reiche, Myrthe E., den Toom, Myrthe, Beckers, Linda, Gijbels, Marion J. J., Gerdes, Norbert, de Winther, Menno P. J., Lutgens, Esther |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086432/ https://www.ncbi.nlm.nih.gov/pubmed/30096208 http://dx.doi.org/10.1371/journal.pone.0202150 |
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