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Atypical CT findings of pulmonary sarcoidosis: A case report
RATIONALE: Pulmonary involvement occurs in about 90% of patients with sarcoidosis. However, delayed diagnosis sometimes occurs due to atypical thoracic imaging findings. PATIENT CONCERNS: A 52-year-old woman presented with recurrent uveitis and fever of unknown origin. She had been admitted to the h...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086523/ https://www.ncbi.nlm.nih.gov/pubmed/30024519 http://dx.doi.org/10.1097/MD.0000000000011456 |
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author | Lee, Han Na Kim, Jung Im Won, Kyuyeoun Song, Ran |
author_facet | Lee, Han Na Kim, Jung Im Won, Kyuyeoun Song, Ran |
author_sort | Lee, Han Na |
collection | PubMed |
description | RATIONALE: Pulmonary involvement occurs in about 90% of patients with sarcoidosis. However, delayed diagnosis sometimes occurs due to atypical thoracic imaging findings. PATIENT CONCERNS: A 52-year-old woman presented with recurrent uveitis and fever of unknown origin. She had been admitted to the hospital due to fever, but its cause was not determined. DIAGNOSES: Chest computed tomography (CT) revealed a solitary pulmonary nodule and an enlarged right axillary lymph node. The nodule had showed an interval growth from 0.7 cm to 1.1 cm over 18 months, when compared to the previous chest CT. Mosaic attenuation was also observed. INTERVENTIONS: The patient underwent thoracoscopic wedge resection of the nodule and excisional biopsy of the enlarged lymph node to exclude malignancy and non-caseating granulomas consistent with sarcoidosis was confirmed. OUTCOMES: Medical treatment with prednisolone and azathioprine was administered. Fever and uveitis no longer recurred after 6 months of medication. We demonstrated that sarcoidosis shows only atypical pulmonary imaging findings, with an enlarged solitary nodule, an axillary lymphadenopathy, and mosaic attenuation, mimicking a malignancy. LESSONS: Awareness on atypical CT manifestations that are correlated with pathologic findings may be helpful for early diagnosis of sarcoidosis. |
format | Online Article Text |
id | pubmed-6086523 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-60865232018-08-17 Atypical CT findings of pulmonary sarcoidosis: A case report Lee, Han Na Kim, Jung Im Won, Kyuyeoun Song, Ran Medicine (Baltimore) Research Article RATIONALE: Pulmonary involvement occurs in about 90% of patients with sarcoidosis. However, delayed diagnosis sometimes occurs due to atypical thoracic imaging findings. PATIENT CONCERNS: A 52-year-old woman presented with recurrent uveitis and fever of unknown origin. She had been admitted to the hospital due to fever, but its cause was not determined. DIAGNOSES: Chest computed tomography (CT) revealed a solitary pulmonary nodule and an enlarged right axillary lymph node. The nodule had showed an interval growth from 0.7 cm to 1.1 cm over 18 months, when compared to the previous chest CT. Mosaic attenuation was also observed. INTERVENTIONS: The patient underwent thoracoscopic wedge resection of the nodule and excisional biopsy of the enlarged lymph node to exclude malignancy and non-caseating granulomas consistent with sarcoidosis was confirmed. OUTCOMES: Medical treatment with prednisolone and azathioprine was administered. Fever and uveitis no longer recurred after 6 months of medication. We demonstrated that sarcoidosis shows only atypical pulmonary imaging findings, with an enlarged solitary nodule, an axillary lymphadenopathy, and mosaic attenuation, mimicking a malignancy. LESSONS: Awareness on atypical CT manifestations that are correlated with pathologic findings may be helpful for early diagnosis of sarcoidosis. Wolters Kluwer Health 2018-07-20 /pmc/articles/PMC6086523/ /pubmed/30024519 http://dx.doi.org/10.1097/MD.0000000000011456 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 |
spellingShingle | Research Article Lee, Han Na Kim, Jung Im Won, Kyuyeoun Song, Ran Atypical CT findings of pulmonary sarcoidosis: A case report |
title | Atypical CT findings of pulmonary sarcoidosis: A case report |
title_full | Atypical CT findings of pulmonary sarcoidosis: A case report |
title_fullStr | Atypical CT findings of pulmonary sarcoidosis: A case report |
title_full_unstemmed | Atypical CT findings of pulmonary sarcoidosis: A case report |
title_short | Atypical CT findings of pulmonary sarcoidosis: A case report |
title_sort | atypical ct findings of pulmonary sarcoidosis: a case report |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086523/ https://www.ncbi.nlm.nih.gov/pubmed/30024519 http://dx.doi.org/10.1097/MD.0000000000011456 |
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