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Structure of the human volume regulated anion channel

SWELL1 (LRRC8A) is the only essential subunit of the Volume Regulated Anion Channel (VRAC), which regulates cellular volume homeostasis and is activated by hypotonic solutions. SWELL1, together with four other LRRC8 family members, potentially forms a vastly heterogeneous cohort of VRAC channels wit...

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Detalles Bibliográficos
Autores principales:	Kefauver, Jennifer M, Saotome, Kei, Dubin, Adrienne E, Pallesen, Jesper, Cottrell, Christopher A, Cahalan, Stuart M, Qiu, Zhaozhu, Hong, Gunhee, Crowley, Christopher S, Whitwam, Tess, Lee, Wen-Hsin, Ward, Andrew B, Patapoutian, Ardem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Structural Biology and Molecular Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086657/ https://www.ncbi.nlm.nih.gov/pubmed/30095067 http://dx.doi.org/10.7554/eLife.38461

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