Accelerated pharmaceutical protein development with integrated cell free expression, purification, and bioconjugation

The use of living cells for the synthesis of pharmaceutical proteins, though state-of-the-art, is hindered by its lengthy process comprising of many steps that may affect the protein’s stability and activity. We aimed to integrate protein expression, purification, and bioconjugation in small volumes...

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Detalles Bibliográficos
Autores principales: Richardson, Dominique, Itkonen, Jaakko, Nievas, Julia, Urtti, Arto, Casteleijn, Marco G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086869/
https://www.ncbi.nlm.nih.gov/pubmed/30097621
http://dx.doi.org/10.1038/s41598-018-30435-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086869/
https://www.ncbi.nlm.nih.gov/pubmed/30097621
http://dx.doi.org/10.1038/s41598-018-30435-4

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