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Accelerated pharmaceutical protein development with integrated cell free expression, purification, and bioconjugation
The use of living cells for the synthesis of pharmaceutical proteins, though state-of-the-art, is hindered by its lengthy process comprising of many steps that may affect the protein’s stability and activity. We aimed to integrate protein expression, purification, and bioconjugation in small volumes...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086869/ https://www.ncbi.nlm.nih.gov/pubmed/30097621 http://dx.doi.org/10.1038/s41598-018-30435-4 |