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Computer-Guided Surface Engineering for Enzyme Improvement

Protein engineering strategies are often guided by our understanding of how the structure of a protein determines its function. However, our understanding is generally restricted to small regions of a protein, namely the active site and its immediate vicinity, while the remainder of the protein is s...

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Detalles Bibliográficos
Autores principales: Wilding, Matthew, Scott, Colin, Warden, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086876/
https://www.ncbi.nlm.nih.gov/pubmed/30097591
http://dx.doi.org/10.1038/s41598-018-30434-5