Nuclear-resident RIG-I senses viral replication inducing antiviral immunity

The nucleus represents a cellular compartment where the discrimination of self from non-self nucleic acids is vital. While emerging evidence establishes a nuclear non-self DNA sensing paradigm, the nuclear sensing of non-self RNA, such as that from nuclear-replicating RNA viruses, remains unexplored...

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Detalles Bibliográficos
Autores principales: Liu, GuanQun, Lu, Yao, Thulasi Raman, Sathya N., Xu, Fang, Wu, Qi, Li, Zhubing, Brownlie, Robert, Liu, Qiang, Zhou, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086882/
https://www.ncbi.nlm.nih.gov/pubmed/30097581
http://dx.doi.org/10.1038/s41467-018-05745-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086882/
https://www.ncbi.nlm.nih.gov/pubmed/30097581
http://dx.doi.org/10.1038/s41467-018-05745-w

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