Arrhythmic hazard map for a 3D whole‐ventricle model under multiple ion channel block

BACKGROUND AND PURPOSE: To date, proposed in silico models for preclinical cardiac safety testing are limited in their predictability and usability. We previously reported a multi‐scale heart simulation that accurately predicts arrhythmogenic risk for benchmark drugs. EXPERIMENTAL APPROACH: We creat...

Descripción completa

Detalles Bibliográficos
Autores principales: Okada, Jun‐ichi, Yoshinaga, Takashi, Kurokawa, Junko, Washio, Takumi, Furukawa, Tetsushi, Sawada, Kohei, Sugiura, Seiryo, Hisada, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086978/
https://www.ncbi.nlm.nih.gov/pubmed/29745425
http://dx.doi.org/10.1111/bph.14357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086978/
https://www.ncbi.nlm.nih.gov/pubmed/29745425
http://dx.doi.org/10.1111/bph.14357

Ejemplares similares