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Insulin-Like Growth Factor-I as an Effector Element of the Cytokine IL-4 in the Development of a Leishmania major Infection

Certain cytokines modulate the expression of insulin-like growth factor- (IGF-) I. Since IL-4 and IGF-I promote growth of the protozoan Leishmania major, we here addressed their interaction in downregulating the expression of Igf-I mRNA using small interfering RNA (siRNA) in Leishmania major-infecte...

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Detalles Bibliográficos
Autores principales:	Reis, Luiza C., Ramos-Sanchez, Eduardo Milton, Petitto-Assis, Fabricio, Nerland, Audun H., Hernandez-Valladares, Maria, Selheim, Frode, Floeter-Winter, Lucile Maria, Goto, Hiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6087592/ https://www.ncbi.nlm.nih.gov/pubmed/30150896 http://dx.doi.org/10.1155/2018/9787128

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