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T Cell Receptor-Independent, CD31/IL-17A-Driven Inflammatory Axis Shapes Synovitis in Juvenile Idiopathic Arthritis
T cells are considered autoimmune effectors in juvenile idiopathic arthritis (JIA), but the antigenic cause of arthritis remains elusive. Since T cells comprise a significant proportion of joint-infiltrating cells, we examined whether the environment in the joint could be shaped through the inflamma...
Autores principales: | Ferguson, Ian D., Griffin, Patricia, Michel, Joshua J., Yano, Hiroshi, Gaffen, Sarah L., Mueller, Robert G., Dvergsten, Jeffrey A., Piganelli, Jon D., Rosenkranz, Margalit E., Kietz, Daniel A., Vallejo, Abbe N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6087740/ https://www.ncbi.nlm.nih.gov/pubmed/30127787 http://dx.doi.org/10.3389/fimmu.2018.01802 |
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