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Effect of a formal oncofertility program on fertility preservation rates—first year experience

BACKGROUND: A formal fertility preservation program was initiated at our institution in 2016 as part of a multi-disciplinary oncofertility initiative to improve the reproductive needs of oncologic patients. After 1 year of initial experience, we assessed sperm banking rates in men diagnosed with can...

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Autores principales: Lopategui, Diana M., Ibrahim, Emad, Aballa, Teodoro C., Brackett, Nancy L., Yechieli, Raphael, Barredo, Julio C., Ramasamy, Ranjith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6087850/
https://www.ncbi.nlm.nih.gov/pubmed/30159232
http://dx.doi.org/10.21037/tau.2018.04.24
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author Lopategui, Diana M.
Ibrahim, Emad
Aballa, Teodoro C.
Brackett, Nancy L.
Yechieli, Raphael
Barredo, Julio C.
Ramasamy, Ranjith
author_facet Lopategui, Diana M.
Ibrahim, Emad
Aballa, Teodoro C.
Brackett, Nancy L.
Yechieli, Raphael
Barredo, Julio C.
Ramasamy, Ranjith
author_sort Lopategui, Diana M.
collection PubMed
description BACKGROUND: A formal fertility preservation program was initiated at our institution in 2016 as part of a multi-disciplinary oncofertility initiative to improve the reproductive needs of oncologic patients. After 1 year of initial experience, we assessed sperm banking rates in men diagnosed with cancer, as well as examined the trends in the use of fertility preservation services. METHODS: We performed a chart review from 2011 to 2017 for men newly diagnosed with cancer, and for all men who underwent fertility preservation during that period of time at our institution. We assessed the rates of sperm banking among patients newly diagnosed with cancer, before and after the implementation of a standardized oncofertility program in 2016. The program includes nursing and physician education regarding indications of fertility preservation. Additionally, we evaluated the overall population undergoing sperm cryopreservation at our institution during the study period. RESULTS: From 2011 to 2016, 30 of 902 oncologic patients underwent sperm banking prior to their treatment (3.3% of total cancer patients). After the program was implemented, 42 of 218 patients underwent fertility preservation between June 2016 and August 2017 (19.3% of total cancer patients). In this group, patients’ mean age was 30.14 years old (range, 13–69 years old), with 6 pediatric patients; 36 of the samples (85.7%) were obtained from masturbation. When viable sperm could not be obtained from ejaculation, patients underwent either testicular or epididymal sperm extraction (6 cases). Overall, 98 men used the formal fertility preservation service. Of these, 42 were cancer patients and 56 were non-cancer patients. Of the non-cancer patients, 17 banked sperm after varicocelectomy, 6 prior to vasectomy and 6 because of hypogonadism. CONCLUSIONS: Rate of sperm banking increased nearly six-fold after institution of a formal fertility preservation program, indicating the clinical need for such a program at academic institutions. Oncofertility is a relevant part of the care for oncologic patients, and should be considered as part of counseling before cancer treatment.
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spelling pubmed-60878502018-08-29 Effect of a formal oncofertility program on fertility preservation rates—first year experience Lopategui, Diana M. Ibrahim, Emad Aballa, Teodoro C. Brackett, Nancy L. Yechieli, Raphael Barredo, Julio C. Ramasamy, Ranjith Transl Androl Urol Original Article BACKGROUND: A formal fertility preservation program was initiated at our institution in 2016 as part of a multi-disciplinary oncofertility initiative to improve the reproductive needs of oncologic patients. After 1 year of initial experience, we assessed sperm banking rates in men diagnosed with cancer, as well as examined the trends in the use of fertility preservation services. METHODS: We performed a chart review from 2011 to 2017 for men newly diagnosed with cancer, and for all men who underwent fertility preservation during that period of time at our institution. We assessed the rates of sperm banking among patients newly diagnosed with cancer, before and after the implementation of a standardized oncofertility program in 2016. The program includes nursing and physician education regarding indications of fertility preservation. Additionally, we evaluated the overall population undergoing sperm cryopreservation at our institution during the study period. RESULTS: From 2011 to 2016, 30 of 902 oncologic patients underwent sperm banking prior to their treatment (3.3% of total cancer patients). After the program was implemented, 42 of 218 patients underwent fertility preservation between June 2016 and August 2017 (19.3% of total cancer patients). In this group, patients’ mean age was 30.14 years old (range, 13–69 years old), with 6 pediatric patients; 36 of the samples (85.7%) were obtained from masturbation. When viable sperm could not be obtained from ejaculation, patients underwent either testicular or epididymal sperm extraction (6 cases). Overall, 98 men used the formal fertility preservation service. Of these, 42 were cancer patients and 56 were non-cancer patients. Of the non-cancer patients, 17 banked sperm after varicocelectomy, 6 prior to vasectomy and 6 because of hypogonadism. CONCLUSIONS: Rate of sperm banking increased nearly six-fold after institution of a formal fertility preservation program, indicating the clinical need for such a program at academic institutions. Oncofertility is a relevant part of the care for oncologic patients, and should be considered as part of counseling before cancer treatment. AME Publishing Company 2018-07 /pmc/articles/PMC6087850/ /pubmed/30159232 http://dx.doi.org/10.21037/tau.2018.04.24 Text en 2018 Translational Andrology and Urology. All rights reserved.
spellingShingle Original Article
Lopategui, Diana M.
Ibrahim, Emad
Aballa, Teodoro C.
Brackett, Nancy L.
Yechieli, Raphael
Barredo, Julio C.
Ramasamy, Ranjith
Effect of a formal oncofertility program on fertility preservation rates—first year experience
title Effect of a formal oncofertility program on fertility preservation rates—first year experience
title_full Effect of a formal oncofertility program on fertility preservation rates—first year experience
title_fullStr Effect of a formal oncofertility program on fertility preservation rates—first year experience
title_full_unstemmed Effect of a formal oncofertility program on fertility preservation rates—first year experience
title_short Effect of a formal oncofertility program on fertility preservation rates—first year experience
title_sort effect of a formal oncofertility program on fertility preservation rates—first year experience
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6087850/
https://www.ncbi.nlm.nih.gov/pubmed/30159232
http://dx.doi.org/10.21037/tau.2018.04.24
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