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Culture-Expanded Human Invariant Natural Killer T Cells Suppress T-Cell Alloreactivity and Eradicate Leukemia

Graft-versus-host disease (GVHD) is a major cause of significant morbidity and mortality after allogeneic hematopoietic cell transplantation (HCT). Invariant natural killer T (iNKT) cells are potent regulators of immune responses, protect from lethal GVHD, and promote graft-versus-leukemia effects i...

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Detalles Bibliográficos
Autores principales: Schmid, Hannes, Schneidawind, Corina, Jahnke, Simona, Kettemann, Felix, Secker, Kathy-Ann, Duerr-Stoerzer, Silke, Keppeler, Hildegard, Kanz, Lothar, Savage, Paul B., Schneidawind, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088196/
https://www.ncbi.nlm.nih.gov/pubmed/30127790
http://dx.doi.org/10.3389/fimmu.2018.01817