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Investigating the Behavior of Published PAINS Alerts Using a Pharmaceutical Company Data Set

[Image: see text] Biochemical assay interference is becoming increasingly recognized as a significant waste of resource in drug discovery, both in industry and academia. A seminal publication from Baell and Holloway raised the awareness of this issue, and they published a set of alerts to identify w...

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Detalles Bibliográficos
Autores principales: Vidler, Lewis R., Watson, Ian A., Margolis, Brandon J., Cummins, David J., Brunavs, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088356/
https://www.ncbi.nlm.nih.gov/pubmed/30128069
http://dx.doi.org/10.1021/acsmedchemlett.8b00097