Mutation burden and other molecular markers of prognosis in colorectal cancer treated with curative intent: results from the QUASAR 2 clinical trial and an Australian community-based series

BACKGROUND: Molecular indicators of colorectal cancer prognosis have been assessed in several studies, but most analyses have been restricted to a handful of markers. We aimed to identify prognostic biomarkers for colorectal cancer by sequencing panels of multiple driver genes. METHODS: In stage II...

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Detalles Bibliográficos
Autores principales: Domingo, Enric, Camps, Carme, Kaisaki, Pamela J, Parsons, Marie J, Mouradov, Dmitri, Pentony, Melissa M, Makino, Seiko, Palmieri, Michelle, Ward, Robyn L, Hawkins, Nicholas J, Gibbs, Peter, Askautrud, Hanne, Oukrif, Dahmane, Wang, Haitao, Wood, Joe, Tomlinson, Evie, Bark, Yasmine, Kaur, Kulvinder, Johnstone, Elaine C, Palles, Claire, Church, David N, Novelli, Marco, Danielsen, Havard E, Sherlock, Jon, Kerr, David, Kerr, Rachel, Sieber, Oliver, Taylor, Jenny C, Tomlinson, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088509/
https://www.ncbi.nlm.nih.gov/pubmed/30042065
http://dx.doi.org/10.1016/S2468-1253(18)30117-1

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