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Extended Intravitreal Rabbit Eye Residence of Nanoparticles Conjugated With Cationic Arginine Peptides for Intraocular Drug Delivery: In Vivo Imaging

PURPOSE: Drug delivery by intravitreal injection remains problematic, small agents and macromolecules both clearing rapidly. Typical carriers use microparticles (>2 μm), with size-related liabilities, to slow diffusion. We recently described cationic nanoparticles (NP) where conjugated Arg peptid...

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Detalles Bibliográficos
Autores principales:	Melgar-Asensio, Ignacio, Kandela, Irawati, Aird, Fraser, Darjatmoko, Soesiawati R., de los Rios, Cristobal, Sorenson, Christine M., Albert, Daniel M., Sheibani, Nader, Henkin, Jack
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2018
Materias:	Retina
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088811/ https://www.ncbi.nlm.nih.gov/pubmed/30098194 http://dx.doi.org/10.1167/iovs.18-24087

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