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Novel endocrine therapeutic strategy in endometrial carcinoma targeting estrogen-related receptor α by XCT790 and siRNA
PURPOSE: To explore the targeted therapy of estrogen-related receptor α (ERRα) in endometrial cancer (EC) cells and its potential mechanisms. METHODS: The mRNA and protein expression levels of ERRα and estrogen receptor α (ERα) were detected by qPCR and Western blotting in RL-952, AN3-CA, HEC-1A, an...
Autores principales: | Sun, PengMing, Mao, XiaoDan, Gao, Min, Huang, MeiMei, Chen, LiLi, Ruan, GuanYu, Huang, WeiYi, Braicu, Elena Ioana, Sehouli, Jalid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089116/ https://www.ncbi.nlm.nih.gov/pubmed/30127640 http://dx.doi.org/10.2147/CMAR.S168043 |
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