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Novel endocrine therapeutic strategy in endometrial carcinoma targeting estrogen-related receptor α by XCT790 and siRNA

PURPOSE: To explore the targeted therapy of estrogen-related receptor α (ERRα) in endometrial cancer (EC) cells and its potential mechanisms. METHODS: The mRNA and protein expression levels of ERRα and estrogen receptor α (ERα) were detected by qPCR and Western blotting in RL-952, AN3-CA, HEC-1A, an...

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Detalles Bibliográficos
Autores principales: Sun, PengMing, Mao, XiaoDan, Gao, Min, Huang, MeiMei, Chen, LiLi, Ruan, GuanYu, Huang, WeiYi, Braicu, Elena Ioana, Sehouli, Jalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089116/
https://www.ncbi.nlm.nih.gov/pubmed/30127640
http://dx.doi.org/10.2147/CMAR.S168043

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