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Vacuolar ATPase as a potential therapeutic target and mediator of treatment resistance in cancer

Vacuolar ATPase (V‐ATPase) is an ATP‐dependent H(+)‐transporter that pumps protons across intracellular and plasma membranes. It consists of a large multi‐subunit protein complex and influences a wide range of cellular processes. This review focuses on emerging evidence for the roles for V‐ATPase in...

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Detalles Bibliográficos
Autores principales: Whitton, Bradleigh, Okamoto, Haruko, Packham, Graham, Crabb, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089187/
https://www.ncbi.nlm.nih.gov/pubmed/29926527
http://dx.doi.org/10.1002/cam4.1594