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Vacuolar ATPase as a potential therapeutic target and mediator of treatment resistance in cancer
Vacuolar ATPase (V‐ATPase) is an ATP‐dependent H(+)‐transporter that pumps protons across intracellular and plasma membranes. It consists of a large multi‐subunit protein complex and influences a wide range of cellular processes. This review focuses on emerging evidence for the roles for V‐ATPase in...
Autores principales: | Whitton, Bradleigh, Okamoto, Haruko, Packham, Graham, Crabb, Simon J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089187/ https://www.ncbi.nlm.nih.gov/pubmed/29926527 http://dx.doi.org/10.1002/cam4.1594 |
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