Identification of Positively and Negatively Selected Driver Gene Mutations Associated With Colorectal Cancer With Microsatellite Instability

BACKGROUND & AIMS: Recent studies have shown that cancers arise as a result of the positive selection of driver somatic events in tumor DNA, with negative selection playing only a minor role, if any. However, these investigations were concerned with alterations at nonrepetitive sequences and did...

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Detalles Bibliográficos
Autores principales: Jonchere, Vincent, Marisa, Laetitia, Greene, Malorie, Virouleau, Alain, Buhard, Olivier, Bertrand, Romane, Svrcek, Magali, Cervera, Pascale, Goloudina, Anastasia, Guillerm, Erell, Coulet, Florence, Landman, Samuel, Ratovomanana, Toky, Job, Sylvie, Ayadi, Mira, Elarouci, Nabila, Armenoult, Lucile, Merabtene, Fatiha, Dumont, Sylvie, Parc, Yann, Lefèvre, Jérémie H., André, Thierry, Fléjou, Jean-François, Guilloux, Agathe, Collura, Ada, de Reyniès, Aurélien, Duval, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089198/
https://www.ncbi.nlm.nih.gov/pubmed/30116770
http://dx.doi.org/10.1016/j.jcmgh.2018.06.002

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