Efficacy and tolerance of early administration of tranexamic acid in patients with cirrhosis presenting with acute upper gastrointestinal bleeding: a study protocol for a multicentre, randomised, double-blind, placebo-controlled trial (the EXARHOSE study)

INTRODUCTION: The management of acute upper gastrointestinal bleeding (UGIB) is challenging in patients with cirrhosis, as it is responsible for severe complications and high mortality rates. Tranexamic acid (TXA) may help control the bleeding by counterbalancing cirrhosis-related hyperfibrinolysis....

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Detalles Bibliográficos
Autores principales: Heidet, Matthieu, Amathieu, Roland, Audureau, Etienne, Augusto, Oriane, Nicolazo de Barmon, Violaine, Rialland, Amandine, Schmitz, David, Pierrang, François, Marty, Jean, Chollet-Xémard, Charlotte, Thirion, Olivier, Jacob, Line
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Gastroenterology and Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089293/
https://www.ncbi.nlm.nih.gov/pubmed/30099397
http://dx.doi.org/10.1136/bmjopen-2018-021943

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