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Myocardin-Related Transcription Factors and SRF are required for cytoskeletal dynamics, invasion and experimental metastasis

Rho GTPases control cytoskeletal dynamics through cytoplasmic effectors, and regulate transcriptional activation by the Myocardin Related Transcription Factors (MRTFs), coactivators for Serum Response Factor (SRF). We used RNAi to investigate the contribution of the MRTF-SRF pathway to cytoskeletal...

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Detalles Bibliográficos
Autores principales: Medjkane, Souhila, Perez-Sanchez, Cristina, Gaggioli, Cedric, Sahai, Erik, Treisman, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089348/
https://www.ncbi.nlm.nih.gov/pubmed/19198601
http://dx.doi.org/10.1038/ncb1833