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Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across eukaryotes

HAPLESS2 (HAP2) is a broadly conserved, gamete-expressed transmembrane protein that was shown recently to be structurally homologous to viral class II fusion proteins, which initiate fusion with host cells via insertion of fusion loops into the host membrane. However, the functional conformation of...

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Detalles Bibliográficos
Autores principales:	Fedry, Juliette, Forcina, Jennifer, Legrand, Pierre, Péhau-Arnaudet, Gérard, Haouz, Ahmed, Johnson, Mark, Rey, Felix A., Krey, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089408/ https://www.ncbi.nlm.nih.gov/pubmed/30102690 http://dx.doi.org/10.1371/journal.pbio.2006357

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