Cargando…

Linarin prevents LPS-induced acute lung injury by suppressing oxidative stress and inflammation via inhibition of TXNIP/NLRP3 and NF-κB pathways

Acute lung injury (ALI) is an important cause of morbidity and mortality for critically ill patients, and linarin (LR) may be a potential treatment for ALI as it reportedly has antioxidant, anti-inflammatory and apoptotic-regulating activity. In the present study, the authors report that saline and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Xiang, Wu, Yi-Chen, Meng, Min, Sun, Qing-Song, Gao, Su-Min, Sun, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089707/ https://www.ncbi.nlm.nih.gov/pubmed/29845284 http://dx.doi.org/10.3892/ijmm.2018.3710

Ejemplares similares

Luteolin Improves Cyclophosphamide-Induced Cystitis through TXNIP/NLRP3 and NF-κB Pathways
por: Zhang, Hengshuai, et al.
Publicado: (2021)

CVB3 Inhibits NLRP3 Inflammasome Activation by Suppressing NF-κB Pathway and ROS Production in LPS-Induced Macrophages
por: Wang, Yanqi, et al.
Publicado: (2023)

Oroxindin inhibits macrophage NLRP3 inflammasome activation in DSS-induced ulcerative colitis in mice via suppressing TXNIP-dependent NF-κB pathway
por: Liu, Qi, et al.
Publicado: (2020)

Corilagin Restrains NLRP3 Inflammasome Activation and Pyroptosis through the ROS/TXNIP/NLRP3 Pathway to Prevent Inflammation
por: Luo, Tianyu, et al.
Publicado: (2022)

Inhibiting TLR4 signaling by linarin for preventing inflammatory response in osteoarthritis
por: Qi, Weihui, et al.
Publicado: (2021)

Thioredoxin-1 distinctly promotes NF-κB target DNA binding and NLRP3 inflammasome activation independently of Txnip
por: Muri, Jonathan, et al.
Publicado: (2020)

N-Lobe of TXNIP Is Critical in the Allosteric Regulation of NLRP3 via TXNIP Binding
por: Cheng, Fengyu, et al.
Publicado: (2022)

BHBA Suppresses LPS-Induced Inflammation in BV-2 Cells by Inhibiting NF-κB Activation
por: Fu, Shou-Peng, et al.
Publicado: (2014)

Preparation and pharmacokinetics in vivo of linarin solid dispersion and liposome
por: Huang, Yingying, et al.
Publicado: (2022)

Anti-Inflammation and Anti-Pyroptosis Activities of Mangiferin via Suppressing NF-κB/NLRP3/GSDMD Signaling Cascades
por: Feng, Min, et al.
Publicado: (2022)

RKC-B1 Blocks Activation of NF-κB and NLRP3 Signaling Pathways to Suppress Neuroinflammation in LPS-Stimulated Mice
por: Liu, Man, et al.
Publicado: (2021)

TXNIP/TRX/NF-κB and MAPK/NF-κB pathways involved in the cardiotoxicity induced by Venenum Bufonis in rats
por: Bi, Qi-rui, et al.
Publicado: (2016)

Jinmaitong Ameliorates Diabetic Peripheral Neuropathy Through Suppressing TXNIP/NLRP3 Inflammasome Activation In The Streptozotocin-Induced Diabetic Rat Model
por: Sun, Qing, et al.
Publicado: (2019)

Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock
por: Mao, Kairui, et al.
Publicado: (2013)

TXNIP Participated in NLRP3-Mediated Inflammation in a Rat Model of Cervical Spondylotic Myelopathy
por: Liu, Peisheng, et al.
Publicado: (2022)

Linarin Inhibits the Acetylcholinesterase Activity In-vitro and Ex-vivo
por: Feng, Xinchi, et al.
Publicado: (2015)

Effects of Piperine on the Intestinal Permeability and Pharmacokinetics of Linarin in Rats
por: Feng, Xinchi, et al.
Publicado: (2014)

Role of ASM/Cer/TXNIP signaling module in the NLRP3 inflammasome activation
por: Jiang, Jianjun, et al.
Publicado: (2021)

(+)-JQ1 attenuated LPS-induced microglial inflammation via MAPK/NFκB signaling
por: Wang, Huanhuan, et al.
Publicado: (2018)

Linarin Enriched Extract Attenuates Liver Injury and Inflammation Induced by High-Fat High-Cholesterol Diet in Rats
por: Zhuang, Zhen-Jie, et al.
Publicado: (2017)

Role of TXNIP/NLRP3 in sepsis-induced myocardial dysfunction
por: Yang, Chun, et al.
Publicado: (2019)

Neobavaisoflavone ameliorates LPS-induced RAW264.7 cell inflammations by suppressing the activation of NF-κB and MAPKs signaling pathways
por: Yuan, Qing, et al.
Publicado: (2022)

Smilax guianensis Vitman Extract Prevents LPS-Induced Inflammation by Inhibiting the NF-κB Pathway in RAW 264.7 Cells
por: Kim, Ju Gyeong, et al.
Publicado: (2020)

Punicalagin Attenuates LPS-Induced Inflammation and ROS Production in Microglia by Inhibiting the MAPK/NF-κB Signaling Pathway and NLRP3 Inflammasome Activation
por: Lo, Jung, et al.
Publicado: (2022)

Neoagaro-oligosaccharide monomers inhibit inflammation in LPS-stimulated macrophages through suppression of MAPK and NF-κB pathways
por: Wang, Wei, et al.
Publicado: (2017)

Sophorolipid Suppresses LPS-Induced Inflammation in RAW264.7 Cells through the NF-κB Signaling Pathway
por: Xu, Ruiqi, et al.
Publicado: (2022)

Brazilein Suppresses Inflammation through Inactivation of IRAK4-NF-κB Pathway in LPS-Induced Raw264.7 Macrophage Cells
por: Kim, Kui-Jin, et al.
Publicado: (2015)

Carvacrol Alleviates Hyperuricemia-Induced Oxidative Stress and Inflammation by Modulating the NLRP3/NF-κB Pathwayt
por: Riaz, Muhammad, et al.
Publicado: (2022)

Orientin Ameliorates LPS-Induced Inflammatory Responses through the Inhibitory of the NF-κB Pathway and NLRP3 Inflammasome
por: Xiao, Qingfei, et al.
Publicado: (2017)

Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-κB signaling and NLRP3 activation
por: Zhang, Bo, et al.
Publicado: (2017)

Taxifolin Suppresses Inflammatory Responses of High-Glucose-Stimulated Mouse Microglia by Attenuating the TXNIP–NLRP3 Axis
por: Iwasa, Masayo, et al.
Publicado: (2023)

Selenium suppressed the LPS‐induced inflammation of bovine endometrial epithelial cells through NF‐κB and MAPK pathways under high cortisol background
por: Cui, Luying, et al.
Publicado: (2023)

Epigenetic regulation of TXNIP-mediated oxidative stress and NLRP3 inflammasome activation contributes to SAHH inhibition-aggravated diabetic nephropathy
por: Dai, Xin, et al.
Publicado: (2021)

Activation of LRP1 Ameliorates Cerebral Ischemia/Reperfusion Injury and Cognitive Decline by Suppressing Neuroinflammation and Oxidative Stress through TXNIP/NLRP3 Signaling Pathway in Mice
por: Yang, Cheng-Jie, et al.
Publicado: (2022)

The Phenolic Fraction of Mentha haplocalyx and Its Constituent Linarin Ameliorate Inflammatory Response through Inactivation of NF-κB and MAPKs in Lipopolysaccharide-Induced RAW264.7 Cells
por: Chen, Xiangyang, et al.
Publicado: (2017)

Deficient chaperone-mediated autophagy facilitates LPS-induced microglial activation via regulation of the p300/NF-κB/NLRP3 pathway
por: Wu, Jin, et al.
Publicado: (2023)

Caffeine Inhibits NLRP3 Inflammasome Activation by Suppressing MAPK/NF-κB and A2aR Signaling in LPS-Induced THP-1 Macrophages
por: Zhao, Weiming, et al.
Publicado: (2019)

LincRNA-Gm4419 knockdown ameliorates NF-κB/NLRP3 inflammasome-mediated inflammation in diabetic nephropathy
por: Yi, Hong, et al.
Publicado: (2017)

Ticagrelor and clopidogrel suppress NF-κB signaling pathway to alleviate LPS-induced dysfunction in vein endothelial cells
por: Jia, Zhuyin, et al.
Publicado: (2019)

Anti-diabetic effects of linarin from Chrysanthemi Indici Flos via AMPK activation
por: Wang, Zhenji, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_h58qkvqs86ce6u1j4tseirngmg