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Moderate correlation between systemic IL‐6 responses and CRP with trough concentrations of voriconazole
AIMS: Voriconazole (VCZ) exhibits wide intrapatient pharmacokinetic variability, which is disadvantageous because of its narrow therapeutic range. A considerable part of this variation remains unexplainable, despite extensive knowledge of this drug. It is hypothesized that inflammation has an impact...
Autores principales: | Vreugdenhil, Bas, van der Velden, Walter J. F. M., Feuth, Ton, Kox, Matthijs, Pickkers, Peter, van de Veerdonk, Frank L., Blijlevens, Nicole M. A., Brüggemann, Roger J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089823/ https://www.ncbi.nlm.nih.gov/pubmed/29744898 http://dx.doi.org/10.1111/bcp.13627 |
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