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Physiologically‐based pharmacokinetic model of vaginally administered dapivirine ring and film formulations

AIMS: A physiologically‐based pharmacokinetic (PBPK) model of the vaginal space was developed with the aim of predicting concentrations in the vaginal and cervical space. These predictions can be used to optimize the probability of success of vaginally administered dapivirine (DPV) for HIV preventio...

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Detalles Bibliográficos
Autores principales:	Kay, Katherine, Shah, Dhaval K., Rohan, Lisa, Bies, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089833/ https://www.ncbi.nlm.nih.gov/pubmed/29714824 http://dx.doi.org/10.1111/bcp.13625

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