Bifidobacterium breve MRx0004 protects against airway inflammation in a severe asthma model by suppressing both neutrophil and eosinophil lung infiltration

Asthma is a phenotypically heterogeneous disease. In severe asthma, airway inflammation can be predominantly eosinophilic, neutrophilic, or mixed. Only a limited number of drug candidates are in development to address this unmet clinical need. Live biotherapeutics derived from the gut microbiota are...

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Detalles Bibliográficos
Autores principales: Raftis, Emma J., Delday, Margaret I., Cowie, Philip, McCluskey, Seánín M., Singh, Mark D., Ettorre, Anna, Mulder, Imke E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089914/
https://www.ncbi.nlm.nih.gov/pubmed/30104645
http://dx.doi.org/10.1038/s41598-018-30448-z

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