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Drug-based perturbation screen uncovers synergistic drug combinations in Burkitt lymphoma
Burkitt lymphoma (BL) is a highly aggressive B-cell lymphoma associated with MYC translocation. Here, we describe drug response profiling of 42 blood cancer cell lines including 17 BL to 32 drugs targeting key cancer pathways and provide a systematic study of drug combinations in BL cell lines. Base...
Autores principales: | Tomska, K., Kurilov, R., Lee, K. S., Hüllein, J., Lukas, M., Sellner, L., Walther, T., Wagner, L., Oleś, M., Brors, B., Huber, W., Zenz, T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089937/ https://www.ncbi.nlm.nih.gov/pubmed/30104685 http://dx.doi.org/10.1038/s41598-018-30509-3 |
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